{"id":313134,"date":"2024-09-04T12:17:33","date_gmt":"2024-09-04T12:17:33","guid":{"rendered":"https:\/\/www.nahrungsmittel-intoleranz.com\/non-celiac-gluten-sensitivity\/"},"modified":"2024-09-04T12:23:17","modified_gmt":"2024-09-04T12:23:17","slug":"non-celiac-gluten-sensitivity","status":"publish","type":"page","link":"https:\/\/www.nahrungsmittel-intoleranz.com\/en\/non-celiac-gluten-sensitivity\/","title":{"rendered":"Non-celiac wheat sensitivity"},"content":{"rendered":"\n<p><strong>Non-celiac gluten sensitivity <\/strong>(NCGS) has been discussed since the early 200s.\nOriginally, it was thought to be a condition in which those affected experience symptoms from eating gluten without suffering from <a href=\"https:\/\/flexikon.doccheck.com\/de\/Z%C3%B6liakie#:~:text=1.-,Definition,intestinalen%20Unvertr%C3%A4glichkeit%20gegen%C3%BCber%20den%20Getreideeiwei%C3%9Fen.\" target=\"_blank\" rel=\"noreferrer noopener\">coeliac disease <\/a>or a wheat <sup>allergy1<\/sup>.\nIt is also sometimes referred to as non-celiac disease non-wheat allergy sensitivity.\nOther triggers have also been considered, not just gluten.\nFODMAPs, ATI or various protein components have been and are being discussed <sup>2-4<\/sup>.\nAnother hypothesis is that a <a href=\"https:\/\/www.nahrungsmittel-intoleranz.com\/en\/leaky-gut-syndrome\/\" target=\"_blank\" rel=\"noreferrer noopener\">weakened intestinal barrier<\/a> could play a <sup>role5<\/sup>.     <\/p>\n\n<p>The current guideline on celiac disease therefore recommends using the term <strong>non-celiac wheat sensitivity<\/strong> (NZWS) instead of non-celiac gluten sensitivity (NZGS) <sup>6.<\/sup><\/p>\n\n<h1 class=\"wp-block-heading\" id=\"h-was-lost-nun-die-beschwerden-aus\">So what triggers the complaints?<\/h1>\n<div class=\"wp-block-image\">\n<figure class=\"alignleft size-full is-resized\"><img decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/www.nahrungsmittel-intoleranz.com\/wp-content\/uploads\/NcihtZoeliakieWeizenSensitivitaet.jpg\" alt=\"Image for post, created by Bing AI, 4.9.2024, 14:14\" class=\"wp-image-313131\" style=\"object-fit:cover;width:415px;height:200px\" srcset=\"https:\/\/www.nahrungsmittel-intoleranz.com\/wp-content\/uploads\/NcihtZoeliakieWeizenSensitivitaet.jpg 1024w, https:\/\/www.nahrungsmittel-intoleranz.com\/wp-content\/uploads\/NcihtZoeliakieWeizenSensitivitaet-300x300.jpg 300w, https:\/\/www.nahrungsmittel-intoleranz.com\/wp-content\/uploads\/NcihtZoeliakieWeizenSensitivitaet-150x150.jpg 150w, https:\/\/www.nahrungsmittel-intoleranz.com\/wp-content\/uploads\/NcihtZoeliakieWeizenSensitivitaet-768x768.jpg 768w, https:\/\/www.nahrungsmittel-intoleranz.com\/wp-content\/uploads\/NcihtZoeliakieWeizenSensitivitaet-100x100.jpg 100w, https:\/\/www.nahrungsmittel-intoleranz.com\/wp-content\/uploads\/NcihtZoeliakieWeizenSensitivitaet-500x500.jpg 500w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n<p>This remains the subject of scientific debate.\nSo far, we only know that the symptoms are not triggered by a single substance such as gluten, FODMAPs, ATI or fructans.\nHowever, we also know that the one-sided avoidance of these substances is more bad than good for those affected.\nFor example, those on a low FODMAP diet may experience short-term improvement, but their quality of life is severely (and unnecessarily) restricted and the gut microbiome is <sup>impoverished7<\/sup>.\nIn the long term, this does more harm than good.    <\/p>\n\n<p>It has often been recommended to use old wheat varieties such as spelt, einkorn or emmer instead of highly cultivated wheat.\nHowever, there is no scientific evidence to support this <sup>recommendation8<\/sup>. <\/p>\n\n<h1 class=\"wp-block-heading\" id=\"h-diagnose-und-therapie\">Diagnosis and therapy<\/h1>\n\n<p>The diagnosis of NCGS is difficult as there is no specific test for it.\nIt is a diagnosis of exclusion, in which coeliac <sup>disease6<\/sup> and wheat allergy must first be ruled out.\nThe diagnosis is often made when symptoms improve on a gluten-free diet and reappear after the reintroduction of gluten-containing foods.\nIn addition, a food and symptom diary should be kept to &#8220;identify reproducible correlations [&#8230;]&#8221;<sup>6<\/sup>.   <\/p>\n\n<p>The recommendation for therapy is currently an individualized nutritional therapy.\nThis involves developing a symptom-oriented diet &#8220;with avoidance or reduction of individually relevant trigger factors &#8220;<sup>6<\/sup> that is individually tailored to the person affected.\nHowever, this therapy only works in cooperation with a state-recognized and well-trained nutritionist and is associated with costs.\nA strict avoidance diet of certain ingredients is not recommended by the specialist associations.   <\/p>\n\n<h3 class=\"wp-block-heading\" id=\"h-quellen\">Sources<\/h3>\n\n<p class=\"smalldark\">1 Reese, I.  <em>et al.<\/em>  Non-celiac gluten\/wheat sensitivity (NCGS)-a currently undefined disorder without validated diagnostic criteria and of unknown prevalence: Position statement of the task force on food allergy of the German Society of Allergology and Clinical Immunology (DGAKI). \n<em>Allergo J. Int.<\/em> <strong>27<\/strong>, 147-151 (2018). <br\/>2 Biesiekierski, J. R.  <em>et al.<\/em>  No Effects of Gluten in Patients With Self-Reported Non-Celiac Gluten Sensitivity After Dietary Reduction of Fermentable, Poorly Absorbed, Short-Chain Carbohydrates. \n<em>Gastroenterology<\/em> <strong>145<\/strong>, 320-328.e3 (2013). <br\/>3 Dale, H. F., Hatlebakk, J. G., Hovdenak, N., Ystad, S. O. &amp; Lied, G. A. The effect of a controlled gluten challenge in a group of patients with suspected non-coeliac gluten sensitivity: A randomized, double-blind placebo-controlled challenge.  <em>Neurogastroenterol.\nMotil. <\/em> <strong>30<\/strong>, e13332 (2018).<br\/>4. Nordin, E., Brunius, C., Landberg, R. &amp; Hellstr\u00f6m, P. M. Fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial.  <em>Am. J. Clin.\nNutr. <\/em> <strong>115<\/strong>, 344-352 (2022).<br\/>5 Uhde, M.  <em>et al.<\/em>  Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease. \n<em>Gut<\/em> <strong>65<\/strong>, 1930-1937 (2016). <br\/>6 Felber, J.  <em>et al.<\/em>  Updated S2k guideline coeliac disease of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS): December 2021 &#8211; AWMF register number: 021-021. \n<em>Z. For Gastroenterol.<\/em> <strong>60<\/strong>, 790-856 (2022). <br\/>7 Schumann, D.  <em>et al.<\/em>  Low fermentable, oligo-, di-, mono-saccharides and polyol diet in the treatment of irritable bowel syndrome: A systematic review and meta-analysis. \n<em>Nutrition<\/em> <strong>45<\/strong>, 24-31 (2018). <br\/>8 Zimmermann, J., Longin, F. H., Schweinlin, A., Basrai, M. &amp; Bischoff, S. C. No Difference in Tolerance between Wheat and Spelt Bread in Patients with Suspected Non-Celiac Wheat Sensitivity. \n<em>Nutrients<\/em> <strong>14<\/strong>, 2800 (2022). <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Non-celiac gluten sensitivity (NCGS) has been discussed since the early 200s. Originally, it was thought to be a condition in which those affected experience symptoms from eating gluten without suffering from coeliac disease or a wheat allergy1. It is also sometimes referred to as non-celiac disease non-wheat allergy sensitivity. Other triggers have also been considered, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":313132,"parent":0,"menu_order":22,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_lmt_disableupdate":"","_lmt_disable":"","wprm-recipe-roundup-name":"","wprm-recipe-roundup-description":"","footnotes":""},"class_list":["post-313134","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Non-celiac wheat sensitivity &#8211; nmi-Portal \u2013 Ern\u00e4hrung im Fokus<\/title>\n<meta name=\"description\" content=\"What is Non-celiac wheat sensitivity? - Click here &amp; find out everything about Non-celiac wheat sensitivity\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.nahrungsmittel-intoleranz.com\/en\/non-celiac-gluten-sensitivity\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Non-celiac wheat sensitivity\" \/>\n<meta property=\"og:description\" content=\"What is Non-celiac wheat sensitivity? 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